Impact of human leukocyte antigen mismatch on lung transplant outcome†
نویسندگان
چکیده
منابع مشابه
Human leukocyte antigen class II antibodies and transplant outcome.
During recent years, increasing evidence has accumulated that preformed antidonor human leukocyte antigen (HLA) class II antibodies represent significant risk factors for transplant dysfunction and failure (1– 6). Also, the posttransplant development of anticlass II antibodies is associated with a higher incidence of acute and chronic rejection (7–14). In this issue, the report by Issa et al. (...
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OBJECTIVES Although previous studies have investigated the effect of human leukocyte antigen matching on long-term outcomes after heart transplants, its role in the prognosis after a heart transplant remains unclear, particularly with respect to short-term survival. MATERIALS AND METHODS We evaluated the human leukocyte antigen mismatch on in-hospital mortality of 158 consecutive patients who...
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Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The human leucocyte antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...
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BACKGROUND Natural immunity against cytomegalovirus (CMV) can control virus replication after solid organ transplantation; however, it is not known which components of the adaptive immune system mediate this protection. We investigated whether this protection requires human leukocyte antigen (HLA) matching between donor and recipient by exploiting the fact that, unlike transplantation of other ...
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ژورنال
عنوان ژورنال: Interactive CardioVascular and Thoracic Surgery
سال: 2018
ISSN: 1569-9293,1569-9285
DOI: 10.1093/icvts/ivx412